हे guys, in the devil may cry ANIME, does Virgil ever make an appearance या is he even meantioned at all?

Vergil does not make an appearance, as the ऐनीमे takes place between the game timelines of 1 and 4 - thus, Vergil has already been defeated (If आप remember, Nelo Angelo - who is actually Vergil - in the first game apparently explodes during the final confrontation).