I don't think so...
MMMMmmm... but this IS good thinking, you got me wondering!

Kakashi would probaly kill himself before killing his comrads

Kakashi would never kill his comrads teamwork is what he stands for.

If Naruto/Sasuke/Sakura was trying to destroy the village like Orochimaru was, and they no longer cared about teamwork, I think Kakashi would put the many lives of the village before his teamwork. I don't think he would put the whole village's safety at risk rather than killing a former student who no longer cared about team work...

After all, Kakashi is quite responsible and...it's not rly disobeying teamwork or what he stands for if he kills someone who no longer cares about that value and is trying to destroy the village... :S

Actually that does happen really, he did have to kill sasuke and got very close to doing so but the fight got interupted. heres a website you can visit to watch full episode (english subbed);
link

(episode 214 and manga chapter 483-484)

WARNING: BIG SPOILER!!!!!; THIS IS ONE OF NARUTO'S LAST EPISODES SO IF YOU WANT TO WATCH IT I WOULD RECCEMEND YOU TO FIRST WATCH (OR READ) ALL THE EPISODES(OR CHAPTERS) BEFORE IT SO IT DOESN'T BECOME A BIG SPOILER. BUT USE THE SAME WEBSITE IF WATCHING IT HAS ALL OF THEM SUBBED.

oh yeah there are also some fan animation based on the fight which just put more on the fight than there already is. here.

and here is part 2.