I think that Alex and Izzie will get another chance as a couple.

i want meredith and derek back together, but i don't know if it will happen. i think they still want eachother, and maybe at the end there will be a kiss or something. i don't kow because the possibilities are endless:)

And I hope that Izzie and Alex get back together :D

never expect the expected

I really hope Alex and Izzie and Derek and Meredeth get back together. If they both did it would be a prefect season for me.

I agree with GA-19 get prepared for something unexpected, because they always like to shake things up on season enders.

alex and izzie!!! *jumps up and down with joy

George and Izzie, best couple on Earth!

Gizzie back together FINALLY

Gizzie love!

Here's my prediction: George comes out as a big gay intern and falls in love with McSteamy. McSteamy dumps George for giving him syph. George is also hurt and decides to join the military. Izzie become overwrought at the news of George's coming out and decides to go on an LVAT cord cutting rampage around the hospital. Meanwhile, Erica and Cristina bond (both being hardcore surgeons) and they unintentionally fall in love with eachother. Bailey and her hubby smooth things over - because they are both hot. Addison comes back to Seattle because Private Practice is cancelled. She decides she wants Derek back and tries her hardest to increase the odds that Derek will choose her. Nurse Rose mysteriously becomes sick and almost dies. Rose finds new meaning in life and decides to leave the nursehood and join the Redcross. The Chief is offered a job as the Dean of Medicine at Harvard thus Burke comes back to fill his shoes. Surprised that Cristina has decided to bat for the other team, he decides to fly the rainbow pride flag along side the American flag outside the hospital as a gesture to win back Cristina. Cristina is unimpressed. Meanwhile, Derek doesn't want Addison back, so she goes for the hotter man, Burke. Burke and Addison have a healthy relationship. Meredith decides to get plastic surgery to smooth out the wrinkles, but McSteamy botches her surgery and thus she goes into hiding never to be seen again. Lexi takes the lead.

George and Izzie get together for good this time

George and Izzie NEED to be back together or I will go nuts

Gizzie Gizzie Gizzie!

Gizzie sounds like Gizzard which apart of the digest tract found in birds. Do you know what stuff in the gizzard eventually becomes? POOP! Poop to the fuggly overly dramatic couple known as gizzie.

Gizzie they are the best couple in the world, no to Merder (do you know in French merde means sh*t) and Lexzieyuck, Gizzie rules the world

O'Stevens (George and Izzie) forever

I want George and Izzie together

I do too

George and Izzie will finally get their chance, I hope

I want Gizzie together

Gizzie Gizzie Gizzie

I want Gizzie back together

George and Izzie back together, I hope

Gizzie together, please please please

I pray that George and Izzie will be reunited

Gizzie love!

I never really know what to expect on this show

Please get Gizzie together

Gizzie together, one can hope

omg this is going to make me sick! the couples that need to be reunited is alex and izzie and mer and der! we need to get the show back to the glory days of season 2! note there was no gizzie then, why you ask, hmm because the show was good then! i would like to see burke come back though, you can tell hes gone and he was neevr one of my favorite characters! which is why im so happy addison is coming back, and onecrew83 love your story!

Season 2 was good but Lexziepuke almost ruined it, I had to start taping and stopped watching live as I kept going to the bathroom to puke seeing them. Thankfully their sex fiasco debacle of a relationshiop was painfully short and she hooked up with Denny. Season 2 was great because of MerDer and Dizzie, lexzie did not last very long, thank God, and it was also great because we got our first hints of Gizzie. Them flirting at the lunch table about making love, Izzie talking about him all the time and getting so jealous of Callie, Izzie talking to Denny about George, we got MerDer, Dizzie and hints of Gizzie and a lot of them together and a few very painful Lexziepuke scene. Also season 2 was good because people were happy. Season 3 was bad but saved only by the beauty that was the Gizzie love story, most of my friends only stuck around for them. If Lexziepuke comes back, we will all quit in droves.

Ok so Gizzie love is in the air. However, I don't think they will get back together. Season 2 was definetly the best and I can't wait to see what happpens.

I want Gizzie together but Shonda is such an idiot, that probably will not happen. Heck, I willn just find another show, Gizzie is way too good a couple for Grey and the only good thing on it

Gizzie love forever, no Gizzie no me

Gizzie forever

I am pretty sure MerDer will happen again but other than that...anything could happen. I bet Izzie and George will break up...I hope so. I'm not saying I'm not a fan but George and Izzie are just BEST FRIENDS!!!

No George and Izzie are in love, only a blind eprson could not see how they look at each other with total and complete love, a friend does not make you light up like that

MerDer are boring, Gizzie is the best couple

Hopefully Gizzie and MerDer will be together

And jarawr, I respect your opinion but to me and many people, George and Izzie are IN LOVE not just best friends

I hope Gizzie will be back together, best couple ever, and yep they are in love, it is obvious

I want Gizzie together

I want Gizzie together

I want Gizzie together, but not sure it will happen, but I want it so bad

I don't know what will happen, but I want George and Izzie together

want Gizzie together but I don't think I will get my wish

I want Gizzie together too, stupid Shonda

In my dreams at least

It won't happen but it is what I want with all my heart

I know this won't happen, stupid Shonda, but this is what I would want to happen

I just want Gizzie together

I hope against hope that we will get Gizzie

I want lots and lots of Gizzie

Gizzie please

I want George and Izzie together so badly

I want Gizzie