Shiro from Deadman Wonderland. She had to keep getting shots everyday,and when they found out she can use blood as a weapon,they cut her arms a lot and made her bleed,so she can use the blood.
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I just thought about her...She really went through a lot in her childhood ..
Ultear Milkovich from Fairy Tail they told her that her mom left her in a basement where they did experiments with humans, they wanted her because she had a lot of magic power inside her. U_U
The main cast of Qualidea Code. Modifications from the true Unknown is what gave them their powers(called World). And that's not even taking into account the final stages of what the Unknown planned to do with them and other kids.....