There are soooooo many amazing ऐनीमे best friends. But I find the relationship between Souji Okita and Hijikata Toshizo of Peacemaker Kurogane to be a thing of beauty. Hijikata has a course, heated, oppressive and grim personality. Okita is kind, gentle, loving and level-headed. And yet, these two have never once argued या fought. Okita tames the beast in Hijikata. And Hijikata protects Okita. And yes, both of these characters are male! And they are based off of real, Shinsengumi Edo period samurai! Their friendship was beautiful in Peacemaker. I wonder if it was true of real life?
Satoshi-kun (Ash) and पिकाचू of course!,they're the closest of फ्रेंड्स as anyone!,they have a great friend relationship,they've had their good times and bad times,but still they've accomplished so much together it's hard not say they aren't amazing friends!