Seriously?! This is one of the most orignal plots i'd ever seen in anime. आप dont see many ऐनीमे with alchemy well like NONE. Most other plos in ऐनीमे are common like Ninjas, shinigami, vampires, werewolves, aliens, ghosts, and a ton more.
Technically its in the मांगा currently, shouldn't be too long before it happens though, but Fairy Tail. 2 Timeskips were used and for no reason but to troll its audience या for the 2nd one, to हटाइए the plot along.